一株具有体外细胞毒抑癌作用的海洋放线菌     

黄耀坚  郑忠辉  曾伟  李军  李力君  苏文金 《海洋学报》2001,23(6):128-132

从厦门海区潮间带江蓠植物中分离到一株链霉菌,其发酵液经体外MTT法和BIA法(生化诱导法)测定,表明具有很高的抑制肿瘤活性,该菌的生物量和抑癌活性与海水基质有关.对分类学特征的研究显示,该菌不同于目前已知的其他放线菌种类,将该菌定为公牛链霉菌海洋变种(Streptomyces tauricus var.marinus).  相似文献   

Buoyancy-driven perturbations in a rapidly rotating,electrically conducting fluid: part II – dynamo action     

Arnaud Chulliat  Hisayoshi Shimizu  David E. Loper 《地球物理与天体物理流体动力学》2013,107(6):471-487

The helicity, electromotive force and α-effect produced in a homogeneous, rapidly rotating, electrically conducting fluid by an isolated source of buoyancy at small Elsasser number are calculated, visualized and analyzed. Due to physical symmetries of the system, the integrals of helicity and electromotive force over all space are zero. However, each has a significant non-zero value when integrated over the cross section of the Taylor column. The local α-effect is found to be significantly anisotropic; it is strongest when the applied magnetic field is toroidal and the resulting EMF is parallel to the applied field.  相似文献   

Maximally-efficient-generation approach in the dynamo theory     

Alexander Ruzmaikin  Anvar Shukurov  Dmitry Sokoloff  Sergey Starchenko 《地球物理与天体物理流体动力学》2013,107(1-3):125-139

Abstract

We propose a method of derivation of global asymptotic solutions of the hydromagnetic dynamo problem at large magnetic Reynolds number. The procedure reduces to matching the local asymptotic forms for the magnetic field generated near individual extrema of generation strength. The basis of the proposed method, named here the Maximally-Efficient-Generation Approach (MEGA), is the assertion that properties of global asymptotic solutions of the kinematic dynamo are determined by the distribution of the generation strength near its leading extrema and by the number and distribution of the extrema.

The general method is illustrated by the global asymptotic solution of the α²-dynamo problem in a slab. The nature of oscillatory solutions revealed earlier in numerical simulations and the reasons for the dominance of even magnetic modes in slab geometry are clarified.

Applicability of the asymptotic solutions at moderate values of the asymptotic parameter is also discussed. We confirm this applicability using comparisons with complementary asymptotic expansions and numerical simulations. In particular, this justifies application of the MEGA solutions to estimation of the generation threshold.  相似文献   

Characterization and expression analysis of an allograft inflammatory factor-1 homologue in yellow grouper (Epinephelus awoara)     

WANG Li  SHI Dawei  WU Xinzhong 《海洋学报(英文版)》2008,27(6):141-148

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基于方向特征显著性计算的MRI脑图像肿瘤检测     

蹇木伟  王瑞红  举雅琨  朱呈瞻  董军宇 《南京气象学院学报》2019,11(6):722-726

本文提出了一种利用方向性特征进行显著性建模的MRI脑图像肿瘤自动检测算法.该模型首先将MRI脑图像进行预处理,去除掉图像中头骨区域的干扰;然后使用基于方向特征的显著性检测增加病变区域的对比度,实现更准确地提取肿瘤图像区域.本文算法在脑图像数据集上进行了大量的实验,并且与主流的肿瘤自动检测方法进行了对比,证明了本文算法的有效性,并为医生提供可靠的辅助诊断和临床参考.  相似文献   

天山山区夏季MαCS时空分布特征     

李建刚  姜彩莲  张云惠  杨莲梅  孙鸣婧 《高原气象》2019,38(3):604-616

利用常规观测、FY-2E卫星及EC-Interim 0.5°×0.5°再分析资料对2010-2014年夏季天山及其两侧地区α中尺度对流系统(MαCS)的时空分布特点进行分析,并对典型个例的云图特征和环境条件进行了深入的探讨。结果表明:(1)6月为MαCS出现的高发期且椭圆形MαCS占多数。MαCS形成和发展期主要集中在午后和后半夜,消亡于前半夜,三个时期最易发生时间依次滞后大约2 h,圆形和椭圆形MαCS日频次分别呈单峰和多峰型变化分布。MαCS生命史主要为3~6 h,其中6月生命史分布较广,7-8月较集中;大部分椭圆形MαCS较圆形MαCS生命史和消亡阶段长,圆形MαCS在形成阶段维持时间较长。(2)MαCS多生成于山边平原或浅山区,并在山区主脉上空形成直至成熟,在河谷和山脉两侧的平原区消亡。MαCS成熟期冷云盖长轴长度集中在500~800 km,云顶面积随MαCS出现频次增加而逐渐减小。圆形MαCS发展期移动缓慢,成熟后移速加快,椭圆形MαCS始终移速较慢。MαCS云团TBBmin呈现单峰型且近似正态分布,圆形较椭圆形MαCS的TBB平均梯度大。(3)天山山区MαCS的形成主要是通过层云中多个独立的β中尺度对流云团合并形成。MαCS易发生在高层急流带的抽吸区以及中层低槽前部的辐合上升区,中低层西南和西北气流携带的充沛水汽在大气不稳定层结、不稳定能量持续聚集的背景下辐合上升,促使MαCS不断发展。  相似文献   

超声与16层螺旋CT在小肝癌诊断中的应用研究   总被引：2，自引：0，他引：2  

戴琳  许乙凯  冯筱榕 《CT理论与应用研究》2006,15(2):52-55

目的:应用超声和16层螺旋CT进行小肝癌联合诊断的对照研究。方法:采用常规超声及高质量扫描模式的16层螺旋CT对18例小肝癌和17例肝脏良性小肿瘤进行对照诊断研究,所有病例均经手术病理或超声引导下穿刺证实。结果:大部分肝脏良恶性小肿瘤在超声图像上有其典型的特征,与CT和病理检查结果相符的有小肝癌14例和良性小肿瘤15例。但,超声诊断怀疑为血管瘤1例和增生结节3例,CT和病理诊断为小肝癌;超声误诊为小肝癌2例而CT和病理均诊断为硬化结节1例,另1例CT诊断与超声相符,但病理确证后为炎性假瘤。结论:超声是肝脏常规检查的首选方法,对肝脏良恶性肿瘤均有较高的检出率,但对一些不典型病例还需16层螺旋CT和病理检查以做出进一步的定性诊断,提高诊断的准确率,二者联合诊断能提高对肝脏良恶性肿瘤的早期诊断率。  相似文献   

Inhibition of fish nodavirus by gymnemagenol extracted from Gymnema sylvestre     

V.Gopiesh Khanna  K.Kannabiran  V.Sarath Babu  A.S.Sahul Hameed 《中国海洋大学学报(英文版)》2011,10(4):402-408

Viral nervous necrosis(VNN)has emerged to become a major problem in the culture of larval and juvenile marine fish worldwide.Bioactive phytochemicals isolated from commonly available medicinal plants are often screened for their efficacy in controlling fish viral diseases.Occurrence of newer viral strains and resistance to existing antiviral drugs are problems currently as-sociated with treatment of VNN,which necessitates looking for alternate sources for effective antiviral drugs.The aim of the present study was to screen antiviral potential of gymnemagenol(C30H50O4)previously extracted from leaves of Gymnema sylvestre.The fish nodavirus,grouper nervous necrosis virus(GNNV)in infected Sahul Indian Grouper Eye(SIGE)cell lines were used to study the antiviral activity of gymnemagenol under in vitro conditions.The susceptibility of the virus to gymnemagenol was confirmed by measuring the viral titre(TCID50 mL?1)in virus-infected SIGE cells every 24 h.Gymnemagenol at 20 μg mL?1 inhibited the prolifera-tion of GNNV to 53% at the end of the 6th d by inhibiting the proliferation of GNNV-infected SIGE cells.The viable SIGE cells were reduced to 47% as determined by 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide(MTT)assay.The viral titre(TCID50 mL?1)was also reduced to log 2.8 at the end of the 7th d in gymnemagenol-treated SIGE cells after inoculated with GNNV when compared to untreated control SIGE cell viral titre(log 4.1).Based on our results it can be concluded that gymnemagenol could be used as an antiviral agent against GNNV infection.  相似文献   

Non-local memory effects of the electromotive force by fluid motion with helicity and two-dimensional periodicity     

Kumiko Hori  Shigeo Yoshida 《地球物理与天体物理流体动力学》2013,107(6):601-632

In mean-field dynamo theory, the electromotive force term 〈u′ × B′〉 due to small-scale fields connects the small-scale magnetic field with the large-scale field. This term is usually approximated as the α-effect, assumed to be instantaneous in time and local in space. However, the approximation is valid only when the magnetic Reynolds number Rm is much less than unity, and is inappropriate when Rm ? 1, which is the condition satisfied in the Earth's core or solar convection zone. We introduce a function φ _qr as a non-local and non-instantaneous generalization of the usual α-effect and examine its behaviour as a function of Rm in the range 1/64 ≤ Rm ≤ 10 for a kinematic dynamo model. We use the flow of G.O. Roberts 1972 Roberts, GO. 1972. Dynamo action of fluid motions with two-dimensional periodicity. Phil. Trans. Roy. Soc. London Ser. A, 271: 411–454. [Crossref], [Web of Science ®] , [Google Scholar] (Phil, Trans. Roy. Soc. London Ser. A, 1972, 271, 411–454), which is steady and has non-zero helicities and two-dimensional periodicity. As a result, we identify three regions in Rm space according to the behaviour of the function φ _qr : (i) Rm ? 1/4, where the function φ _qr is local and instantaneous and can be approximated by the traditional α and β effects, (ii) 1/4 ? Rm ? 4, where the deviation from the traditional α and β effects increases and non-localness and non-instantaneousness increase, and (iii) Rm ? 4, where boundary layers develop fully and non-localness and non-instantaneousness are prominent. We show that the non-local memory effect for Rm ? 4 strongly affects the dynamo action and explains an observed augmentation of the growth rate in the dispersion relation. The results imply that the non-local memory effect of the electromotive force should be important in the geodynamo or the solar dynamo.  相似文献   

Weakly nonlinear analysis of the  α effect     

D. Gérard-varet 《地球物理与天体物理流体动力学》2013,107(3-4):171-184

We address mathematical issues raised by the so-called α?effect of dynamo theory, which is a dynamo mechanism arising in conducting flows with small scale fluctuations. Analytical results on the α?effect concern the linear induction equation, and are usually claimed to hold for the whole magnetohydrodynamics (MHD) system, as long as the amplitude of the perturbations is small. We discuss the justification of that claim, in the case of periodic fluctuations of the fields. We show a nonlinear instability result on the MHD system, that predicts dynamo action for a large class of high frequency periodic flows, up to the fully nonlinear regime.  相似文献